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In functional mitochondria, the supply of energy substrates is coupled with oxidative phosphorylation, which ensures a complete metabolic pathway for the generation of ATP

The prevalence of CHE was reported to be between 30% and 84% in patients with cirrhosis [7,12,13]

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It is a clinical expression of a spectrum of potentially reversible neuropsychiatric abnormalities secondary to the accumulation of neurotoxic substances in brain tissue that is proportional to the synthetic function and functional reserve of the liver

In 2024, North America accounted for the highest market share at 41.23% and was valued at USD 88.39 Million and is expected to reach USD 119.75 Million in 2032