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This contributes to increased NADPH production and ROS generation, exacerbating oxidative stress and promoting aberrant immune activation (155, 156)

Elife 15, e18489

OS, environmental (e.g., smoking), health (e.g., hypertension, and obesity), and poor diet are factors known to accelerate this shortening, and impact cellular health and the ageing process [25]

[DOI] [PubMed] [Google Scholar] Bodine PV, Stauffer B, Ponce-de-Leon H, Bhat RA, Mangine A, Seestaller-Wehr LM, Moran RA, Billiard J, Fukayama S, Komm BS, et al

In mammalian cells, PrxIV could function in concert with Ero1 and the glutathione peroxidases Gpx7 and 8 to metabolize hydrogen peroxide and to maximize the oxidative power of the reduced oxygen

The effects of N-acetylcysteine on pulmonary functions in patients undergoing on-pump coronary artery surgery: a double blind placebo controlled study
