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In particular, TNF- may have an important role in the initiation and development of intestinal barrier defects in IBD, because anti-TNF- treatment suppresses the inflammatory response and improves intestinal permeability.65 As a consequence of perturbation of multiple cytokines, the alterations to the intestinal TJ structures in IBD patients could be complicated

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J Pain 2021

Zhou B, Feng X, Han C, Wu Y, Qiao J, Tong W, et al

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Liver Health Research The liver is both the primary site of glutathione synthesis and the organ most exposed to toxic compounds and metabolic byproducts