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In cases of pathological inflammation in aortic aneurysms, tissue copper levels are significantly elevated (79)

Phytotherapy Research, 33 (12), 30903111

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This finding is intriguing because human glutathione synthetase deficiency, a heritable amino acid metabolism disorder, also leads to hyperaccumulation of pyroglutamic acid resulting in high anion gap metabolic acidosis a form of acidosis defined by acid accumulation and low pH of the blood 48