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Endocrine (2021) 71(2):45966

Optimizing Ergothioneine Biosynthesis and Antioxidant Activity in Agaricus spp

66 These experiments illustrate the importance of validating potential grafting strategies by demonstrating robust cell survival, host integration, and dopamine release in animal models before clinical trials

Studies observed through two-photon imaging that neurons in awake mice preferentially uptake the glucose analog 2-deoxyglucose-IR (2DG-IR) during sensory stimulation, with higher hexokinase expression than astrocytes, indicating that neurons have an intrinsic ability to metabolize glucose through enhanced glycolysis (Tang, 2018

Therefore, these aforementioned studies suggest that the RNA m 6 A modification is involved in ferroptosis by regulating the mRNA stability and protein expression of multiple ferroptosis-related genes (Figure 4B)

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