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However, one study in particular noted that their cuprizone-containing pellets failed to induce demyelination despite toxicological analysis of the pellets confirming that they still contained active cuprizone 28

62 This presents the opportunity for the development of oral, topical, and injectable formulations, allowing for both whole-body NAD+-restoring benefits alongside more targeted administration, resulting in the ultimate inside-outside approach to aging (Table 2)

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