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PMID: 37682709 Arch Toxicol2020 Oct;94(10):3433-3447

The leaves and stems are usually harvested just before flowering or during flowering

However, the putative liver toxicity of methotrexate should be evaluated in the context of advances in our knowledge of the pathogenesis and natural history of liver disease, especially non-alcoholic fatty liver disease (NAFLD)

However, these findings have not yet been validated in humans, where the established resolutive pathways likely rely on the interplay between neutrophil apoptosis, anti-inflammatory cytokines produced by T reg cells (e.g

Longo R, Peri C, Cricr D, Coppi L, Caruso D, Mitro N, et al

doi: 10.3390/molecules26206109, 101