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J Rheumatol 30(1):146-50, 2003

Effects of Ido1 activity include promotion of T cell- mediated tolerance and antimicrobial effects 154 and Ido1 might also act at the site of expression to decrease T-cell proliferation and survival, diminishing colonic inflammation and reducing disease severity 155

However, this work remains at the experimental stage

Acetogenins induce apoptosis in cancer cells by targeting oxidative phosphorylation and ATP synthesis through the inhibition of mitochondrial complex I and ubiquinone-linked NADH oxidase in the plasma membrane of these cells
[DOI] [PubMed] [Google Scholar] 20.Jo SK, Lee WY, Rhee EJ, et al

Its used when a patient has anemia, but the provider has not yet identified the exact type or cause
