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After multiple once daily dosing of divalproex sodium ER, the peak-to-trough fluctuation in plasma valproate concentrations was 10-20% lower than that of regular divalproex sodium given b.i.d., t.i.d., or q.i.d

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Protein Metabolism*

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Blood samples were collected for safety monitoring

Alongside physical symptoms, the very common chronic inflammatory disease rosacea contributes to increased levels of oxidative stress as well as other pathogenetic factors