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To validate this in NB patient tumors, we used spatial transcriptomic analysis on paired tumor specimens obtained from two high-risk NB patients before and after treatment (Fig

Consequently, these limitations have catalyzed increasing interest in natural metabolites with multi-target pharmacological properties and favorable safety profiles

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Future research on creatine supplementation and kidney function would greatly benefit from standardized reporting of assay type and calibration method, which would enable more precise synthesis of evidence

Opioid receptors, including mu, delta, and kappa receptors, are distributed throughout the nervous system and are involved in pain modulation [14,15,16,17]