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Similarly, activation of Nrf2 was also demonstrated in an in vivo cerebral ischemia model, with increased SOD1 in the nucleus, SOD2, glutathione S-transferase and peroxidase in the cortex, and increased activity of catalase in the striatum, evidencing the protective effects of DATS [157]

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Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis

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