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Description
Due to the requirement of both delivery efficiency and safety, the majority of drug delivery systems with the ability to cross BBB are designed at a nanoscale level with tailored chemical composition and surface properties (Table 2)

Association of metformin use with cancer incidence and mortality: a meta-analysis

NRF2 is a transcription factor that governs the antioxidant pathway by targeting GSH metabolism-related genes 41,49

In the CNS, TNFR2 is predominantly found in neuroglia, with highest expression in microglia (140, 141)

K., et al., Common and Rare Variant Association Analyses in amyotrophic Lateral sclerosis Identify 15 Risk Loci With Distinct Genetic Architectures and Neuronspecific Biology, Nature Genetics 53, no

10.3390/biomedicines9080992 153 KimJ.-Y.KimK.-H.LeeW.-R.AnH.-J.LeeS.-J.HanS.-M.et al (2015a)
