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Prior studies in the Chien lab, consisting of DNA sequence analysis of over 4000 cancer samples, have shown a selection bias against missense mutants carrying the P72 SNP, and cancer patients harboring somatic TP53 mutations in the P72 allele showed improved prognosis [15]

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Perovic D, Kolenc D, Bilic V, Somun N, Drmic D, Elabjer E, et al

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Responses were graded on a 4-point scale: 0, no response

doi: 10.1038/nri3771 17 AlissafiTKalafatiLLazariMFiliaAKloukinaIManifavaMet al
