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Microdosing is helpful in the following conditions: It can be helpful for those who experience intolerable side effects with therapeutic doses

The loss of ADAMTS13 leads to microthrombi and tissue ischemia, and untreated TTP has a 90% fatality rate

2 The British Society for Haematology recommends intramuscular vitamin B 12 for severe deficiency and malabsorption syndromes, whereas oral replacement may be considered for patients with asymptomatic, mild disease with no absorption or compliance concerns

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