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These findings suggest that research into the therapeutic modulation of FOXO4 activity, such as through the use of the synthetic peptide FOXO4-DRI, could provide insight into the heart's natural protective mechanisms and degenerative changes associated with aging

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overexpressed Grx2 in HeLa cells, which caused less sensitivity to doxorubicin and 2-deoxy-D-glucose (2-DG)

[DOI] [PubMed] [Google Scholar] Onodera Y, Motohashi H, Takagi K, Miki Y, Shibahara Y, Watanabe M, Ishida T, Hirakawa H, Sasano H, Yamamoto M, Suzuki T

Although it is unclear if UV-B induces opacification of squirrel lenses, it does cause oxidative stress, shown through increasing lipid peroxidation and a reduction in antioxidant

Phys Rev E Stat Nonlin Soft Matter Phys 76: 031924 Zufall F (2000) The cellular and molecular basis of odor adaptation