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Restoring NAD+ removes this bottleneck

Endogenous aging results from intrinsic factors, including time, genetics, immunity, endocrinology, accumulation of senescent cells, and the senescence-associated secretory phenotype (SASP)

GSTP1 forms a complex with TRAF2 and thereby prevents the formation of TNF--induced TRAF2-ASK1 complex and therefore suppresses the activation of apoptosis signal-regulated kinase 1 (ASK1) [65]

We searched the electronic databases PubMed, Web of Science, Embase, and China National Knowledge Infrastructure database (CNKI), Wanfang up to 18 March 2024 with the key words ulcerative colitis and ferroptosis, ulcerative colitis and traditional Chinese medicine, TCM, or natural plant, etc
