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Middle cerebral artery occlusions performed in Sprague-Dawley rats, produce inflammatory gene expression, including adhesion molecules, in cerebral ischemia, measurable using quantitative real-time RT-PCR analysis

The Hallmarks of Ferroptosis

Sci Rep 10 , 12665 (2020)

Bala et al

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The idea of using spin traps as therapeutic agents arose when -phenyl- tert -butylnitrone (PBN) was shown to have protective effects in various animal models of ischemiareperfusion (including intestinal, cardiac, and cerebral)