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Supplementary Data 4 (download XLSX Statistical supporting data for Supplementary Fig

[DOI] [PubMed] [Google Scholar] Hauge J.G

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Mechanisms of Muscle Hypertrophy IGF-1 DES promotes muscle growth through potent activation of IGF-1 receptors on muscle cells, triggering PI3K/Akt/mTOR pathways mediating protein synthesis, increased amino acid and glucose uptake into myocytes, satellite cell activation and proliferation, inhibition of protein degradation (anti-catabolic effects), and enhanced muscle fiber hypertrophy

At a concentration of 0.5 g/mL, SMN-CeO@G promoted proliferation and reduced apoptosis of ATDC5 chondrocytes while decreasing IL-1-induced MMP-13 secretion
