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Indeed, drug resistance is also related to increase discharge (efflux) of anticancer drugs due to the overexpression of the efflux transporters

doi: 10.3389/fimmu.2020.00300

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Its vital for enzyme-binding spots

If you happen to do this, you'd likely destroy the peptide or make it unstable, so if you're just looking for pure GHK (without the copper), you'd need to buy it that way from the start