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Embryonic oxidative stress as a mechanism of teratogenesis with special emphasis on diabetic embryopathy

References Alba M, Fintini D, Sagazio A, Lawrence B, Castaigne JP, Frohman LA, Salvatori R
In our previous studies with both bulk (Gill et al, 2014) and scRNA-seq (Yuan et al, 2018), we observed that the mesenchymal phenotype was strongly associated with recurrent tumors and that the principal remaining glioma cell type with neural lineage resemblance was astrocyte-like

Pavanello, C

(See Note: Oligosaccharidases ) The action of the four oligosaccharidases generates several monosaccharides

Here, we find that LDHB promotes GSH synthesis and defends against ferroptosis by upregulating SLC7A11, the functional subunit of the cystine/glutamate antiporter system Xc (SLC7A11 and SLC3A2), which takes up extracellular cystine to synthesize the antiferroptotic metabolite GSH [36, 63], a cofactor of GPX4 that neutralizes lipid peroxides and suppresses ferroptosis [33]
