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Heightened inflammation: Dysregulated NF-kB pathways promote pro-inflammatory cytokines

Annals of Surgical Oncology 2011;18:37117

These trials included both single-dose pharmacokinetic studies and long-term efficacy trials extending up to 24 weeks of continuous administration

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But theres no evidence that taking B supplements would prevent these bone problems
My feeling is that if you use any smaller gauge of needle you risk damaging the surrounding tissue at the injection site
