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Epigenetic and MicroRNA Regulation In addition to genetic susceptibility, epigenetic modifications, such as DNA methylation, histone acetylation, and microRNA (miRNA) regulation, play critical roles in the pathogenesis of hypertension-induced kidney injury

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Furthermore, the effects of GHK on astrocyte were associated with the upregulation of miRNA-146a-3p, which partially regulated the expression of AQP4

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[DOI] [PMC free article] [PubMed] [Google Scholar] 142.Pufulete M., Al-Ghnaniem R., Khushal A., Appleby P., Harris N., Gout S., Emery P.W., Sanders T.A