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Moreover neurofibrillary tangles results from aggregation and hyperphosphorylation of tau protein [34]

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The development of optic nerve gliomas in these mice showed that astrocytoma formation requires NF1 heterozygosity and loss of NF1 in astrocytes and highlights this mouse model as one of the few preclinical models available for NF1-associated optic glioma (77)

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Selecting the Right Syringe Size Choose a syringe size appropriate for your dose volume