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Various causes, including exogenous and endogenous stress factors, an imbalance between prooxidants and antioxidants, disruption of antioxidant pathways, and gene polymorphisms, lead to the overproduction of reactive oxygen species

Gastrointestinal cell-line studies involving peptide-mediated regulation

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Research applications include studying how senescent immune cells affect vaccine efficacy, immune surveillance, and infection resistance in aging models, providing insights into interventions for age-related immune decline and immunosenescence mechanisms