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In rodent models examining type 2 diabetes or diet-induced metabolic syndrome, NAC often improves glucose tolerance and reduces fasting blood glucose levels (Figure 1E)

Cell-line selectivity improves the predictive power of pharmacogenomicanalyses and helps identify NADPH as biomarker for ferroptosissensitivity

The metabolic process involves the activity of upstream macromolecules such as DNA and proteins

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[DOI] [PubMed] [Google Scholar] 93.Lin H.Y., Hou S.C., Chen S.C., Kao M.C., Yu C.C., Funayama S., Ho C.T., Way T.D

Therefore, the toxic effects on the thyroid observed for phthalates in human studies cannot rule out the possible contribution of micro- and nanoplastics and/or EDCs, and future studies should also assess the effect of multiple exposures to different contaminants