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This gap partly stems from the traditional reliance on larval models for speed, leaving adult zebrafish underutilized for studies of chronic exposure, cumulative toxicity, and long-term therapeutic efficacy (White and Patton, 2023)
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Chidiac, A

doi: 10.14293/genint.14.1.004
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, sevoflurane) are well known to cause ischemic preconditioning part of this effect is via mild uncoupling of mitochondria and activation of cytoprotective kinases (like PKC-) that ultimately reduce mPTP opening on reperfusion (128, 129)
