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ImmTOR inhibits the development of uricase-specific ADAs in a dose-dependent manner, thus enabling sustained enzyme activity and reduction in serum uric acid levels
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doi:10.17116/jnevro201811811103-109 Richard SA

In order to collect a sufficient number of cells for implantation, isolated chondrocytes usually undergo an extensive expansion from 0.10.2 million to 4060 million (Huang et al., 2016)