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It has been reported that these astrocytes lose their capacity to promote neuronal survival and synaptogenesis and can contribute to neuronal death (Liddelow et al., 2017)

We found that GPX3 inhibits oxidative stress-related pathways (NFB pathway) and apoptosis-related pathways (Caspase pathway) (Figure 3B), which is consistent with our previous results

Wiley, pp 148178

Oligodendroglial fibroblast growth factor receptor 1 gene targeting protects mice from experimental autoimmune encephalomyelitis through ERK/AKT phosphorylation

Audzeyenka I, Rachubik P, Typiak M, Kulesza T, Topolewska A, Rogacka D, et al

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