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OSU-T315 inhibits AKT and induces cell death through autophagy dysregulation in both VS and meningioma, indicating an upregulation of ATG5
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Vitamins are essential for both animals and humans
Ren W, Yang L, Deng T, Wu C, Li Y, Wu J, et al
Curiously, Cys48, Cys102, and Lys103, which were shown to be palmitoylated in vitro , are present in the hydrophobic interface of the dimer, where a lock and key motif is formed by the Tyr50 in the NH 2 -terminus of one monomer, which wedges into a hydrophobic pocket in the COOH-terminus of the other monomer (amino acids 80 to 110) [53]
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