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Peptides bound to the HLA molecules were dissociated upon mild acid elution with 5 ml 10% acetic acid to denature and subunits of MHC molecules

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The resulting effect on cell cycle progression is dependent on a number of factors, including the concentration of cAMP generated

International Journal of Molecular Sciences 21, 1790

Additionally, macrophages enhance ECM deposition which increases the release of proinflammatory cytokines and results in a vicious cycle that perpetuates the inflammatory state [97]
