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Annu Rev Pharmacol Toxicol 32:109134 Lundberg JO, Gladwin MT, Weitzberg E (2015) Strategies to increase nitric oxide signalling in cardiovascular disease

Other studies such as in vitro studies, animal experiments, observational studies, studies with duration below two weeks, case reports and studies without a control group were excluded from this meta-analysis

These therapeutic benefits, coupled with its potential for use in combination therapies, make esculetin a promising candidate for improving asthma management and patient outcomes [102]

In particular, studies used for this review (Quijano et al., 2012

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