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Furthermore, DAG generated by PNPLA2 preferentially produces 1,3- DAG which cannot activate PKC (196), suggesting that the de novo generation of DAGs leads to insulin resistance
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In contrast, in the IMR-5/75 MNA cell line, (M+D)/2 reduced MYCN by half, while (M+D+V)/3 led to an even greater decrease ( Supplementary Figure S7B )
