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Because high xCT levels are associated with poor prognosis in a number of cancer types, including GBM 66 and triple-negative breast cancer 67 , the xCT transporter has been suggested as a therapeutic target for cancer 6769

These safer nutrient stressors likely trigger similar cell-signaling pathways to boost glutathione levels and enhance cellular protection

N-acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntingtons disease

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This is why they are classified by researchers as Growth Hormone Secretagogues (GHSs)