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After CTR1-mediated uptake, copper is bound within the cell to the antioxidant Cu chaperone 1 (ATOX1), which directs Cu + to Cu-transporting P-type ATPases (911)

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The DEGs were significantly enriched in metabolic pathways, protein digestion and absorption, retinol metabolism, MAPK signaling pathway, PI3KAkt signaling pathway, Wnt signaling pathway, PPAR signaling pathway, and TGF-beta signaling pathway (Figure 4A)