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Design considerations and therapeutic potential

Mol Endocrinol (1997) 11(4):3939.10.1210/mend.11.4.9907 25 SilvennoinenOWitthuhnBAQuelleFWClevelandJLYiTIhleJN

Glutamine is required for PKM2KO PDAC defense against cystine starvation induced ferroptosis Given the apparent importance of glutamine metabolism in ferroptosis, we investigated the role of environmental glutamine in PKM2KO mediated defense against ferroptosis

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