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An analysis of GEO data of PD ( n = 128) identified modules associated with RNA metabolism pathology as a potential cause of PD by sorting differentially active pathways between brain transcriptomics samples from PD patients and controls 21,22

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In summary, the NF-B signaling pathway is activated by both AGE and NOX, as well as pro-inflammatory cytokines such as IL-6 or TNF-
