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Carrieri AP, Haiminen N, Maudsley-Barton S, Gardiner LJ, Murphy B, Mayes AE, et al

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The study also found that hydrogen-rich water alleviates intestinal oxidative stress by upregulating the expression of SIRT1, Nrf2, and HO-1, thus activating the SIRT1/Nrf2/HO-1 signaling pathway, which further improves constipation

Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival

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