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In the absence of Smad3, myostatin induces ROS production through the activation of p38 and ERK mitogen-activated protein kinase (MAPK) pathways mediated via TNF-, IL-6 and xanthine oxidase (XO)

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The effect of antioxidants on the properties of red blood cells from patients with sickle cell anemia

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These include patients with impaired renal function due to their inability to adequately clear high IVC doses from circulation, and patients with G6PD deficiency due to inability to detoxify oxidative stress generated by high dose IVC administration

Longevity: Studies have linked higher glutathione levels to increased longevity, making it a potential key player in extending a healthy lifespan
