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Or click one of the links below: Target-CD Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most frequently affecting the bowels

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While oral B12 supplements are available, vitamin B12 injections have advantages including enhanced absorption since it bypasses digestion, a fast-acting energy boost from quick absorption, higher blood levels reached versus pills, lasting benefits between maintenance doses, improved concentration and mental clarity, and often more affordable and convenient long-term

Annual review of nutrition , 21 (1), 407428

Other common causes of vitamin B12 deficiency include gastrectomy, ileal resection, pancreatic insufficiency and malabsorption syndromes including Crohns disease and coeliac disease. The bottom line : for patients with the above gastrointestinal challenges, getting enough B12 into the bloodstream through oral supplementation is not possible