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doi: 10.1073/pnas.0509531103
Therefore, topical NSAIDs may have advantages over oral NSAIDs in some cases (e.g., osteoarthritis)
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PMID: 10541835
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When it misfolds it can form sticky toxic oligomers that clump together to form large insoluble proteins including amyloid fibrils and Lewy bodies , which are a pathophysiological hallmark of Parkinson disease
