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Variances in circadian phase, light responsiveness, and clock gene expression identified between older and younger adults [41], could lead to a different reaction to vitamin B12
(2019) "Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing" Cell and Tissue Research Xing et al

You can, but the vial must be used within 24 hours because sterile water contains no antimicrobial preservative
For twice-daily injections, administer once in the morning and once at night

L., Frederiksen J