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Components of the CS are both enzymes able to catalyze the acyl-CoA + carnitine CoA + acylcarnitines reaction and carrier(s) involved in the bi-directional transport of acyl moieties from cytosol to mitochondria and vice versa

The endogenous biosynthesis which mainly takes place in the liver, kidney, and to some extent in the brain, meets only 25% of the carnitine required by the human body, while the remaining 75% is obtained from the diet under regular diet regimen, i.e., consuming either meat, fish, dairy product, and vegetables (Longo et al., 2006

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Carnitine exists in two forms: D-carnitine and L-carnitine

doi: 10.1111/and.12062 [7] Lenzi A, Lombardo F, Sgr P, Salacone P, Caponecchia L, Dondero F, Gandini L

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