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J Comp Neurol 495(5):529553

Int J Mol Sci, 2015

In severe cases, this can lead to muscle weakness, cramps, and even muscle pain, due to nerve damage from long-term deficiency
Clin Endocrinol (Oxf) (2021) 95:60617

Its all about making therapy fit each patients needs and the reason for their deficiency

Wood JD, Liu S, Drossman DA, Ringel Y, Whitehead WE (2012) Anti-enteric neuronal antibodies and the irritable bowel syndrome