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Myelodysplastic syndromes (MDS) and autoimmune disorders (AD): Cause or consequence

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Zieger, U., Marston, D

doi: 10.2174/092986706776361058 301 SuMNaderiKSamsonNYoussefIFulopLBozsoZet al
However, its essential to highlight that the applicability of these findings from a non-severe mouse model to human patients necessitates further investigation

however, the majority have failed clinical trials due to adverse side effects, which typically include increased blood lipid levels and/or fatty liver, suggesting that prolonged and chronic activation of hepatic GCK adversely affects hepatic lipid metabolism (69, 84)
