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The present results are consistent with Farahat and colleagues , who studied efficacy of topical glutathione cream 2% and reported poor response and Sriharsha and colleagues , who used glutathione soap for 3 months in melasma treatment and reported no significant improvement in the hyperpigmentation in most patients

Although other cell death modalities, such as necroptosis and ferroptosis, were not explored, the authors demonstrated how this apoptotic vulnerability could be exploited

Molecular mechanisms of N-acetylcysteine actions

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