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Description
Across many cancer types, aberrant, constitutively active NRF2-dependent transcription promotes tumor initiation, progression, and therapeutic resistance, and ultimately portends poor clinical outcomes
Front Endocrinol (Lausanne) 16(11):568861 Wang J, Song X, Tan G et al (2021) NAD + improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway

doi:10.1016/j.anai.2011.12.009

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