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acetaminophen-induced hepatic necrosis iv protective role of glutathione In vivo upstream factors mouse hepatotoxic mechanism with sustained depletion: Acetaminophen metabolite-erythrocyte adducts and splenic macrophage-generated reactive oxygen species The Metabolism of Acetaminophen and

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Substantial oxidative stress also occurs in the intestine due to exposure to foreign substances and microbial pathogens [347]

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