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The K1 cell line is a BRAF V600E -PI3KCA mutant, MDA-T32 is a BRAF V600E -TERT promoter mutant, and MDA-T68 is a NRAS and TERT promoter mutant, whereas TPC1 does not possess RAS or BRAF mutations

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Excess iron could promote the Fenton reaction in PD lesions, that is, lead to the production of more ROS, which is unfavorable for the treatment of PD