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we found that in serum levels of BNP and NT-proBNP were significantly decreased in the L-C group compared with those in the control group (WMD: 124.60 pg/ml, 95% CI: 220.49 to 28.71, P = 0.01

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Specifically, we used genetic variants to predict l-carnitine, and obtained their associations with coronary artery disease (CAD), ischemic stroke, heart failure, and atrial fibrillation, as well as CVD risk factors (type 2 diabetes, glucose, HbA1c, insulin, lipid profile, blood pressure and body mass index) in large consortia and established cohorts, as well as sex-specific association in the UK Biobank