l carnitine pancreatic cancer Serum and risk: a Mendelian randomization study identifying cancer as a modifiable metabolic target | Discover Oncology L-Carnitine | CAM Cancer
Description
La funzione pi nota della carnitina quella di navetta per gli acidi grassi a lunga catena: senza questo passaggio, tali acidi non possono entrare nella matrice mitocondriale per essere ossidati
doi: 10.1002/ptr.7543
Transcription factors responsive to cellular energy status can upregulate or downregulate the expression of these genes
Carnitine serves a second critical metabolic function, buffering the Coenzyme A pool against accumulation of short chain acetyl-CoAs, which at increasing levels reduce the activity of the pyuvate dehydrogenase complex (PDC)
It contributes to
